AstraZeneca in Cambridge: The drug giant cut the ribbon on a new $1 billion, 18-story Kendall Square R&D center, adding space for 1,100 workers and expanding its Massachusetts footprint as part of a bigger U.S. investment push. Measles watch in Massachusetts: With measles surging nationally, doctors warn the Bay State could be next, pointing to uneven kindergarten vaccination rates across counties. Winter energy relief: Gov. Healey declared an “energy emergency,” expanding heating help and temporarily reducing some electric-bill charges as costs climb. Opportunity zones reshaped: Healey’s administration submitted a new map that would cut Central Mass. opportunity zones overall, with Worcester gaining one while several towns lose theirs. Health care access in Ware: Baystate Health is set to break ground next month on a new Convenient Care clinic, aiming to restore services after the Mary Lane Hospital closure. Workforce shake-up at HubSpot: Cambridge-based HubSpot plans layoffs of nearly 660 employees as it reorganizes around AI-focused customer outcomes. Local public safety and courts: A judge refused to block a company’s removal from a Worcester apartment project, while police located a truck and identified a driver after a fatal I-93 crash in Wilmington. Education ballot fight: Massachusetts voters face a packed Nov. 3 ballot with nine statewide questions, including major debates over public records and education funding.